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Ultrafast folding kinetics and cooperativity of villin headpiece in single-molecule force spectroscopy

In this study we expand the accessible dynamic range of single-molecule force spectroscopy by optical tweezers to the microsecond range by fast sampling. We are able to investigate a single molecule for up to 15 min and with 300-kHz bandwidth as the protein undergoes tens of millions of folding/unfo...

Täydet tiedot

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Bibliografiset tiedot
Päätekijät: Žoldák, Gabriel, Stigler, Johannes, Pelz, Benjamin, Li, Hongbin, Rief, Matthias
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: National Academy of Sciences 2013
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC3831443/
https://ncbi.nlm.nih.gov/pubmed/24145407
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1311495110
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