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Single-molecule force spectroscopy distinguishes target binding modes of calmodulin
The eukaryotic signaling protein calmodulin (CaM) can bind to more than 300 known target proteins to regulate numerous functions in our body in a calcium-dependent manner. How CaM distinguishes between these various targets is still largely unknown. Here, we investigate fluctuations of the complex f...
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| Hlavní autoři: | , |
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| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
National Academy of Sciences
2009
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2732892/ https://ncbi.nlm.nih.gov/pubmed/19667195 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0904654106 |
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