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On artifacts in single-molecule force spectroscopy

In typical force spectroscopy experiments, a small biomolecule is attached to a soft polymer linker that is pulled with a relatively large bead or cantilever. At constant force, the total extension stochastically changes between two (or more) values, indicating that the biomolecule undergoes transit...

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Detalles Bibliográficos
Publicado en:Proc Natl Acad Sci U S A
Main Authors: Cossio, Pilar, Hummer, Gerhard, Szabo, Attila
Formato: Artigo
Idioma:Inglês
Publicado: National Academy of Sciences 2015
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4655570/
https://ncbi.nlm.nih.gov/pubmed/26540730
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1519633112
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