Extracting Kinetics from Single-Molecule Force Spectroscopy: Nanopore Unzipping of DNA Hairpins

Single-molecule force experiments provide powerful new tools to explore biomolecular interactions. Here, we describe a systematic procedure for extracting kinetic information from force-spectroscopy experiments, and apply it to nanopore unzipping of individual DNA hairpins. Two types of measurements...

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Bibliografiske detaljer
Main Authors: Dudko, Olga K., Mathé, Jérôme, Szabo, Attila, Meller, Amit, Hummer, Gerhard
Format: Artigo
Sprog:Inglês
Udgivet: Biophysical Society 2007
Fag:
Biophysical Theory and Modeling
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1877759/
https://ncbi.nlm.nih.gov/pubmed/17384066
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1529/biophysj.106.102855
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