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Kinetic Ductility and Force-Spike Resistance of Proteins from Single-Molecule Force Spectroscopy

Ductile materials can absorb spikes in mechanical force, whereas brittle ones fail catastrophically. Here we develop a theory to quantify the kinetic ductility of single molecules from force spectroscopy experiments, relating force-spike resistance to the differential responses of the intact protein...

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Detalhes bibliográficos
Publicado no:Biophys J
Main Authors: Cossio, Pilar, Hummer, Gerhard, Szabo, Attila
Formato: Artigo
Idioma:Inglês
Publicado em: The Biophysical Society 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5002075/
https://ncbi.nlm.nih.gov/pubmed/27558726
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2016.05.054
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