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Mechanisms of small molecule–DNA interactions probed by single-molecule force spectroscopy

There is a wide range of applications for non-covalent DNA binding ligands, and optimization of such interactions requires detailed understanding of the binding mechanisms. One important class of these ligands is that of intercalators, which bind DNA by inserting aromatic moieties between adjacent D...

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Podrobná bibliografie
Vydáno v:Nucleic Acids Res
Hlavní autoři: Almaqwashi, Ali A., Paramanathan, Thayaparan, Rouzina, Ioulia, Williams, Mark C.
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2016
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4872107/
https://ncbi.nlm.nih.gov/pubmed/27085806
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkw237
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