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Biophysical characterization of DNA binding from single molecule force measurements
Single molecule force spectroscopy is a powerful method that uses the mechanical properties of DNA to explore DNA interactions. Here we describe how DNA stretching experiments quantitatively characterize the DNA binding of small molecules and proteins. Small molecules exhibit diverse DNA binding mod...
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| Main Authors: | , , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
2010
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2930095/ https://ncbi.nlm.nih.gov/pubmed/20576476 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.plrev.2010.06.001 |
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