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Mechanisms of small molecule–DNA interactions probed by single-molecule force spectroscopy

There is a wide range of applications for non-covalent DNA binding ligands, and optimization of such interactions requires detailed understanding of the binding mechanisms. One important class of these ligands is that of intercalators, which bind DNA by inserting aromatic moieties between adjacent D...

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Publicat a:Nucleic Acids Res
Autors principals: Almaqwashi, Ali A., Paramanathan, Thayaparan, Rouzina, Ioulia, Williams, Mark C.
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2016
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4872107/
https://ncbi.nlm.nih.gov/pubmed/27085806
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkw237
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