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Subnanometre enzyme mechanics probed by single-molecule force spectroscopy

Enzymes are molecular machines that bind substrates specifically, provide an adequate chemical environment for catalysis and exchange products rapidly, to ensure fast turnover rates. Direct information about the energetics that drive conformational changes is difficult to obtain. We used subnanometr...

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Bibliografiske detaljer
Udgivet i:Nat Commun
Main Authors: Pelz, Benjamin, Žoldák, Gabriel, Zeller, Fabian, Zacharias, Martin, Rief, Matthias
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 2016
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4770092/
https://ncbi.nlm.nih.gov/pubmed/26906294
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms10848
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