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Knotting and unknotting of a protein in single molecule experiments

Spontaneous folding of a polypeptide chain into a knotted structure remains one of the most puzzling and fascinating features of protein folding. The folding of knotted proteins is on the timescale of minutes and thus hard to reproduce with atomistic simulations that have been able to reproduce feat...

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Bibliografische gegevens
Gepubliceerd in:Proc Natl Acad Sci U S A
Hoofdauteurs: Ziegler, Fabian, Lim, Nicole C. H., Mandal, Soumit Sankar, Pelz, Benjamin, Ng, Wei-Ping, Schlierf, Michael, Jackson, Sophie E., Rief, Matthias
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: National Academy of Sciences 2016
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4941514/
https://ncbi.nlm.nih.gov/pubmed/27339135
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1600614113
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