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Tightening the Knot in Phytochrome by Single-Molecule Atomic Force Microscopy

A growing number of proteins have been shown to adopt knotted folds. Yet the biological roles and biophysical properties of these knots remain poorly understood. We used protein engineering and atomic force microscopy to explore the single-molecule mechanics of the figure-eight knot in the chromopho...

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Detalhes bibliográficos
Main Authors: Bornschlögl, Thomas, Anstrom, David M., Mey, Elisabeth, Dzubiella, Joachim, Rief, Matthias, Forest, Katrina T.
Formato: Artigo
Idioma:Inglês
Publicado em: The Biophysical Society 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2717258/
https://ncbi.nlm.nih.gov/pubmed/19217867
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2008.11.012
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