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Single-Molecule Unfolding Force Distributions Reveal a Funnel-Shaped Energy Landscape
The protein folding process is described as diffusion on a high-dimensional energy landscape. Experimental data showing details of the underlying energy surface are essential to understanding folding. So far in single-molecule mechanical unfolding experiments a simplified model assuming a force-inde...
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| Main Authors: | , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
Biophysical Society
2006
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1367298/ https://ncbi.nlm.nih.gov/pubmed/16361331 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1529/biophysj.105.077982 |
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