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Exploring the energy landscape of GFP by single-molecule mechanical experiments

We use single-molecule force spectroscopy to drive single GFP molecules from the native state through their complex energy landscape into the completely unfolded state. Unlike many smaller proteins, mechanical GFP unfolding proceeds by means of two subsequent intermediate states. The transition from...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Dietz, Hendrik, Rief, Matthias
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: National Academy of Sciences 2004
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC528946/
https://ncbi.nlm.nih.gov/pubmed/15531635
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0404549101
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