A Rational Approach for the Identification of Non-Hydroxamate HDAC6-Selective Inhibitors

The human histone deacetylase isoform 6 (HDAC6) has been demonstrated to play a major role in cell motility and aggresome formation, being interesting for the treatment of multiple tumour types and neurodegenerative conditions. Currently, most HDAC inhibitors in preclinical or clinical evaluations a...

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Detaylı Bibliyografya
Yayımlandı:Sci Rep
Asıl Yazarlar: Goracci, Laura, Deschamps, Nathalie, Randazzo, Giuseppe Marco, Petit, Charlotte, Dos Santos Passos, Carolina, Carrupt, Pierre-Alain, Simões-Pires, Claudia, Nurisso, Alessandra
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Nature Publishing Group 2016
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4941420/
https://ncbi.nlm.nih.gov/pubmed/27404291
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep29086
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