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A Rational Approach for the Identification of Non-Hydroxamate HDAC6-Selective Inhibitors
The human histone deacetylase isoform 6 (HDAC6) has been demonstrated to play a major role in cell motility and aggresome formation, being interesting for the treatment of multiple tumour types and neurodegenerative conditions. Currently, most HDAC inhibitors in preclinical or clinical evaluations a...
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| Publicado no: | Sci Rep |
|---|---|
| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4941420/ https://ncbi.nlm.nih.gov/pubmed/27404291 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep29086 |
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