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HDAC6 as a target for neurodegenerative diseases: what makes it different from the other HDACs?
Histone deacetylase (HDAC) inhibitors have been demonstrated to be beneficial in animal models of neurodegenerative diseases. Such results were mainly associated with the epigenetic modulation caused by HDACs, especially those from class I, via chromatin deacetylation. However, other mechanisms may...
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| Hauptverfasser: | , , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
BioMed Central
2013
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3615964/ https://ncbi.nlm.nih.gov/pubmed/23356410 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1750-1326-8-7 |
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