Comparative analysis of tumor spheroid generation techniques for differential in vitro drug toxicity

Multicellular tumor spheroids are powerful in vitro models to perform preclinical chemosensitivity assays. We compare different methodologies to generate tumor spheroids in terms of resultant spheroid morphology, cellular arrangement and chemosensitivity. We used two cancer cell lines (MCF7 and OVCA...

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Dades bibliogràfiques
Publicat a:Oncotarget
Autors principals: Raghavan, Shreya, Mehta, Pooja, Horst, Eric N., Ward, Maria R., Rowley, Katelyn R., Mehta, Geeta
Format: Artigo
Idioma:Inglês
Publicat: Impact Journals LLC 2016
Matèries:
Research Paper
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4941362/
https://ncbi.nlm.nih.gov/pubmed/26918944
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.7659
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