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Comparative analysis of tumor spheroid generation techniques for differential in vitro drug toxicity

Multicellular tumor spheroids are powerful in vitro models to perform preclinical chemosensitivity assays. We compare different methodologies to generate tumor spheroids in terms of resultant spheroid morphology, cellular arrangement and chemosensitivity. We used two cancer cell lines (MCF7 and OVCA...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Raghavan, Shreya, Mehta, Pooja, Horst, Eric N., Ward, Maria R., Rowley, Katelyn R., Mehta, Geeta
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4941362/
https://ncbi.nlm.nih.gov/pubmed/26918944
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.7659
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