Personalized Medicine Based Approach to Model Patterns of Chemoresistance, and Tumor Recurrence Using Ovarian Cancer Stem Cell Spheroids

PURPOSE: Chemoresistant ovarian cancers grow in suspension within the ascites fluid. In order to screen the effect of chemotherapeutics and biologics on resistant ovarian cancers with a personalized basis, we developed a 3D hanging drop spheroid platform. EXPERIMENTAL DESIGN: We initiated spheroids...

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Xehetasun bibliografikoak
Argitaratua izan da:Clin Cancer Res
Egile Nagusiak: Raghavan, Shreya, Mehta, Pooja, Ward, Maria R., Bregenzer, Michael E., Fleck, Elyse M. A., Tan, Lijun, McLean, Karen, Buckanovich, Ronald J., Mehta, Geeta
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2017
Gaiak:
Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC6330017/
https://ncbi.nlm.nih.gov/pubmed/28814433
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-17-0133
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