Formation of stable small cell number three-dimensional ovarian cancer spheroids using hanging drop arrays for preclinical drug sensitivity assays

BACKGROUND: Ovarian cancer grows and metastasizes from multicellular spheroidal aggregates within the ascites fluid. Multicellular tumor spheroids are therefore physiologically significant3Din vitro models for ovarian cancer research. Conventional hanging drop cultures require high starting cell num...

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Publicado en:Gynecol Oncol
Main Authors: Raghavan, Shreya, Ward, Maria R., Rowley, Katelyn R., Wold, Rachel M., Takayama, Shuichi, Buckanovich, Ronald J., Mehta, Geeta
Formato: Artigo
Idioma:Inglês
Publicado: 2015
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4480341/
https://ncbi.nlm.nih.gov/pubmed/25913133
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ygyno.2015.04.014
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