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Comparative analysis of tumor spheroid generation techniques for differential in vitro drug toxicity

Multicellular tumor spheroids are powerful in vitro models to perform preclinical chemosensitivity assays. We compare different methodologies to generate tumor spheroids in terms of resultant spheroid morphology, cellular arrangement and chemosensitivity. We used two cancer cell lines (MCF7 and OVCA...

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Bibliografiske detaljer
Udgivet i:Oncotarget
Main Authors: Raghavan, Shreya, Mehta, Pooja, Horst, Eric N., Ward, Maria R., Rowley, Katelyn R., Mehta, Geeta
Format: Artigo
Sprog:Inglês
Udgivet: Impact Journals LLC 2016
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4941362/
https://ncbi.nlm.nih.gov/pubmed/26918944
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.7659
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