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Dynamics of the Tec‐family tyrosine kinase SH3 domains

The Src Homology 3 (SH3) domain is an important regulatory domain found in many signaling proteins. X‐ray crystallography and NMR structures of SH3 domains are generally conserved but other studies indicate that protein flexibility and dynamics are not. We previously reported that based on hydrogen...

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Bibliografske podrobnosti
izdano v:Protein Sci
Main Authors: Roberts, Justin M., Tarafdar, Sreya, Joseph, Raji E., Andreotti, Amy H., Smithgall, Thomas E., Engen, John R., Wales, Thomas E.
Format: Artigo
Jezik:Inglês
Izdano: John Wiley and Sons Inc. 2016
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4941224/
https://ncbi.nlm.nih.gov/pubmed/26808198
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pro.2887
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