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Differential Sensitivity of Src-Family Kinases to Activation by SH3 Domain Displacement
Src-family kinases (SFKs) are non-receptor protein-tyrosine kinases involved in a variety of signaling pathways in virtually every cell type. The SFKs share a common negative regulatory mechanism that involves intramolecular interactions of the SH3 domain with the PPII helix formed by the SH2-kinase...
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| Hauptverfasser: | , , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Public Library of Science
2014
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4140816/ https://ncbi.nlm.nih.gov/pubmed/25144189 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0105629 |
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