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Remodeling of HIV-1 Nef Structure by Src-Family Kinase Binding

The HIV-1 accessory protein Nef controls multiple aspects of the viral life cycle and host immune response, making it an attractive therapeutic target. Previous X-ray crystal structures of Nef in complex with key host cell binding partners have shed light on protein-protein interactions critical to...

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Detalhes bibliográficos
Publicado no:J Mol Biol
Main Authors: Moroco, Jamie A., Alvarado, John Jeff, Staudt, Ryan P., Shi, Haibin, Wales, Thomas E., Smithgall, Thomas E., Engen, John R.
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5801098/
https://ncbi.nlm.nih.gov/pubmed/29258818
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2017.12.008
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