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Recombinant anti-erbB2 immunotoxins containing Pseudomonas exotoxin.

Immunotoxins were made using five different murine monoclonal antibodies to the human erbB2 gene product and LysPE40, a 40-kDa recombinant form of Pseudomonas exotoxin (PE) lacking its cell-binding domain. All five conjugates were specifically cytotoxic to cancer cell lines overexpressing erbB2 prot...

詳細記述

保存先:
書誌詳細
主要な著者: Batra, J K, Kasprzyk, P G, Bird, R E, Pastan, I, King, C R
フォーマット: Artigo
言語:Inglês
出版事項: 1992
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC49398/
https://ncbi.nlm.nih.gov/pubmed/1352878
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