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Mechanisms of Resistance to Immunotoxins Containing Pseudomonas Exotoxin A in Cancer Therapy

Immunotoxins are a class of targeted cancer therapeutics in which a toxin such as Pseudomonas exotoxin A (PE) is linked to an antibody or cytokine to direct the toxin to a target on cancer cells. While a variety of PE-based immunotoxins have been developed and a few have demonstrated promising clini...

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Publicado en:Biomolecules
Autores principales: Dieffenbach, Michael, Pastan, Ira
Formato: Artigo
Lenguaje:Inglês
Publicado: MDPI 2020
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC7408526/
https://ncbi.nlm.nih.gov/pubmed/32630017
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/biom10070979
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