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Renal Excretion of Recombinant Immunotoxins Containing Pseudomonas Exotoxin
Recombinant immunotoxins BL22 (CAT-3888) and LMB-2, composed of Fv fragments of anti-CD22 and CD25 MAbs, respectively, have produced major responses in patients with hematologic malignancies, and are also associated with renal toxicity, particularly with BL22. Characterization of the renal excretion...
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| Опубликовано в: : | Bioconjug Chem |
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| Главные авторы: | , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
2011
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6290476/ https://ncbi.nlm.nih.gov/pubmed/21410247 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bc1005152 |
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