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Renal Excretion of Recombinant Immunotoxins Containing Pseudomonas Exotoxin

Recombinant immunotoxins BL22 (CAT-3888) and LMB-2, composed of Fv fragments of anti-CD22 and CD25 MAbs, respectively, have produced major responses in patients with hematologic malignancies, and are also associated with renal toxicity, particularly with BL22. Characterization of the renal excretion...

Täydet tiedot

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Bibliografiset tiedot
Julkaisussa:Bioconjug Chem
Päätekijät: Traini, Roberta, Kreitman, Robert J
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2011
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC6290476/
https://ncbi.nlm.nih.gov/pubmed/21410247
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bc1005152
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