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Inhibition of SIRT2 suppresses hepatic fibrosis

Liver fibrosis can progress to cirrhosis and result in serious complications of liver disease. The pathogenesis of liver fibrosis involves the activation of hepatic stellate cells (HSCs), the underlying mechanisms of which are not fully known. Emerging evidence suggests that the classic histone deac...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Am J Physiol Gastrointest Liver Physiol
Prif Awduron: Arteaga, Maribel, Shang, Na, Ding, Xianzhong, Yong, Sherri, Cotler, Scott J., Denning, Mitchell F., Shimamura, Takashi, Breslin, Peter, Lüscher, Bernhard, Qiu, Wei
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: American Physiological Society 2016
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4935480/
https://ncbi.nlm.nih.gov/pubmed/27125275
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpgi.00271.2015
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