Suppression of fibrogenic signaling in hepatic stellate cells by Twist1-dependent microRNA-214 expression: Role of exosomes in horizontal transfer of Twist1

A hallmark of liver fibrosis is the activation of hepatic stellate cells (HSC), which results in their production of fibrotic molecules, a process that is largely regulated by connective tissue growth factor (CCN2). CCN2 is increasingly expressed during HSC activation because of diminished expressio...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:Am J Physiol Gastrointest Liver Physiol
Hauptverfasser: Chen, Li, Chen, Ruju, Kemper, Sherri, Charrier, Alyssa, Brigstock, David R.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Physiological Society 2015
Schlagworte:
Liver and Biliary Tract Physiology/Pathophysiology
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4572411/
https://ncbi.nlm.nih.gov/pubmed/26229009
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpgi.00140.2015
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!

Ähnliche Einträge