Inhibition of SIRT2 suppresses hepatic fibrosis

Liver fibrosis can progress to cirrhosis and result in serious complications of liver disease. The pathogenesis of liver fibrosis involves the activation of hepatic stellate cells (HSCs), the underlying mechanisms of which are not fully known. Emerging evidence suggests that the classic histone deac...

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Bibliografske podrobnosti
izdano v:Am J Physiol Gastrointest Liver Physiol
Main Authors: Arteaga, Maribel, Shang, Na, Ding, Xianzhong, Yong, Sherri, Cotler, Scott J., Denning, Mitchell F., Shimamura, Takashi, Breslin, Peter, Lüscher, Bernhard, Qiu, Wei
Format: Artigo
Jezik:Inglês
Izdano: American Physiological Society 2016
Teme:
Liver and Biliary Tract Physiology/Pathophysiology
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4935480/
https://ncbi.nlm.nih.gov/pubmed/27125275
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpgi.00271.2015
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