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Inhibition of SIRT2 suppresses hepatic fibrosis

Liver fibrosis can progress to cirrhosis and result in serious complications of liver disease. The pathogenesis of liver fibrosis involves the activation of hepatic stellate cells (HSCs), the underlying mechanisms of which are not fully known. Emerging evidence suggests that the classic histone deac...

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Detalhes bibliográficos
Publicado no:Am J Physiol Gastrointest Liver Physiol
Main Authors: Arteaga, Maribel, Shang, Na, Ding, Xianzhong, Yong, Sherri, Cotler, Scott J., Denning, Mitchell F., Shimamura, Takashi, Breslin, Peter, Lüscher, Bernhard, Qiu, Wei
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4935480/
https://ncbi.nlm.nih.gov/pubmed/27125275
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpgi.00271.2015
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