Skeletal muscle action of estrogen receptor α is critical for the maintenance of mitochondrial function and metabolic homeostasis in females

Impaired estrogen receptor α(ERα) action promotes obesity and metabolic dysfunction in humans and mice; however, the mechanisms underlying these phenotypes remain unknown. Considering that skeletal muscle is a primary tissue responsible for glucose disposal and oxidative metabolism, we established t...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Sci Transl Med
Prif Awduron: Ribas, Vicent, Drew, Brian G., Zhou, Zhenqi, Phun, Jennifer, Kalajian, Nareg Y., Soleymani, Teo, Daraei, Pedram, Widjaja, Kevin, Wanagat, Jonathan, de Aguiar Vallim, Thomas Q., Fluitt, Amy H., Bensinger, Steven, Le, Thuc, Radu, Caius, Whitelegge, Julian P., Beaven, Simon W., Tontonoz, Peter, Lusis, Aldons J., Parks, Brian W., Vergnes, Laurent, Reue, Karen, Singh, Harpreet, Bopassa, Jean C., Toro, Ligia, Stefani, Enrico, Watt, Matthew J., Schenk, Simon, Akerstrom, Thorbjorn, Kelly, Meghan, Pedersen, Bente K., Hewitt, Sylvia C., Korach, Kenneth S., Hevener, Andrea L.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2016
Pynciau:
Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4934679/
https://ncbi.nlm.nih.gov/pubmed/27075628
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/scitranslmed.aad3815
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