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Skeletal muscle action of estrogen receptor α is critical for the maintenance of mitochondrial function and metabolic homeostasis in females

Impaired estrogen receptor α(ERα) action promotes obesity and metabolic dysfunction in humans and mice; however, the mechanisms underlying these phenotypes remain unknown. Considering that skeletal muscle is a primary tissue responsible for glucose disposal and oxidative metabolism, we established t...

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書誌詳細
出版年:Sci Transl Med
主要な著者: Ribas, Vicent, Drew, Brian G., Zhou, Zhenqi, Phun, Jennifer, Kalajian, Nareg Y., Soleymani, Teo, Daraei, Pedram, Widjaja, Kevin, Wanagat, Jonathan, de Aguiar Vallim, Thomas Q., Fluitt, Amy H., Bensinger, Steven, Le, Thuc, Radu, Caius, Whitelegge, Julian P., Beaven, Simon W., Tontonoz, Peter, Lusis, Aldons J., Parks, Brian W., Vergnes, Laurent, Reue, Karen, Singh, Harpreet, Bopassa, Jean C., Toro, Ligia, Stefani, Enrico, Watt, Matthew J., Schenk, Simon, Akerstrom, Thorbjorn, Kelly, Meghan, Pedersen, Bente K., Hewitt, Sylvia C., Korach, Kenneth S., Hevener, Andrea L.
フォーマット: Artigo
言語:Inglês
出版事項: 2016
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4934679/
https://ncbi.nlm.nih.gov/pubmed/27075628
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/scitranslmed.aad3815
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