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PON2 Deficiency Leads to Increased Susceptibility to Diet-Induced Obesity

(1) Background: Paraoxonase 2 (PON2) is a ubiquitously expressed protein localized to endoplasmic reticulum and mitochondria. Previous studies have shown that PON2 exhibits anti-oxidant and anti-inflammatory functions, and PON2-deficient (PON2-def) mice are more susceptible to atherosclerosis. Furth...

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Detalhes bibliográficos
Publicado no:Antioxidants (Basel)
Main Authors: Shih, Diana M., Meng, Yonghong, Sallam, Tamer, Vergnes, Laurent, Shu, Michelle L., Reue, Karen, Tontonoz, Peter, Fogelman, Alan M., Lusis, Aldons J., Reddy, Srinivasa T.
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2019
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6356528/
https://ncbi.nlm.nih.gov/pubmed/30641857
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/antiox8010019
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