HSP72 Is a Mitochondrial Stress Sensor Critical for Parkin Action, Oxidative Metabolism, and Insulin Sensitivity in Skeletal Muscle

Increased heat shock protein (HSP) 72 expression in skeletal muscle prevents obesity and glucose intolerance in mice, although the underlying mechanisms of this observation are largely unresolved. Herein we show that HSP72 is a critical regulator of stress-induced mitochondrial triage signaling sinc...

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Bibliografische gegevens
Hoofdauteurs: Drew, Brian G., Ribas, Vicente, Le, Jamie A., Henstridge, Darren C., Phun, Jennifer, Zhou, Zhenqi, Soleymani, Teo, Daraei, Pedram, Sitz, Daniel, Vergnes, Laurent, Wanagat, Jonathan, Reue, Karen, Febbraio, Mark A., Hevener, Andrea L.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: American Diabetes Association 2014
Onderwerpen:
Metabolism
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3994950/
https://ncbi.nlm.nih.gov/pubmed/24379352
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/db13-0665
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