Myeloid-specific estrogen receptor α deficiency impairs metabolic homeostasis and accelerates atherosclerotic lesion development

ERα is expressed in macrophages and other immune cells known to exert dramatic effects on glucose homeostasis. We investigated the impact of ERα expression on macrophage function to determine whether hematopoietic or myeloid-specific ERα deletion manifests obesity-induced insulin resistance in mice....

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Detalhes bibliográficos
Main Authors: Ribas, Vicent, Drew, Brian G., Le, Jamie A., Soleymani, Teo, Daraei, Pedram, Sitz, Daniel, Mohammad, Laila, Henstridge, Darren C., Febbraio, Mark A., Hewitt, Sylvia C., Korach, Kenneth S., Bensinger, Steven J., Hevener, Andrea L.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2011
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3182726/
https://ncbi.nlm.nih.gov/pubmed/21900603
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1104533108
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