HSP72 protects against obesity-induced insulin resistance

Patients with type 2 diabetes have reduced gene expression of heat shock protein (HSP) 72, which correlates with reduced insulin sensitivity. Heat therapy, which activates HSP72, improves clinical parameters in these patients. Activation of several inflammatory signaling proteins such as c-jun amino...

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Detalhes bibliográficos
Main Authors: Chung, Jason, Nguyen, Anh-Khoi, Henstridge, Darren C., Holmes, Anna G., Chan, M. H. Stanley, Mesa, Jose L., Lancaster, Graeme I., Southgate, Robert J., Bruce, Clinton R., Duffy, Stephen J., Horvath, Ibolya, Mestril, Ruben, Watt, Matthew J., Hooper, Philip L., Kingwell, Bronwyn A., Vigh, Laszlo, Hevener, Andrea, Febbraio, Mark A.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2008
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2234214/
https://ncbi.nlm.nih.gov/pubmed/18223156
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0705799105
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