Estrogen receptor α protects pancreatic β-cells from apoptosis by preserving mitochondrial function and suppressing endoplasmic reticulum stress

Estrogen receptor α (ERα) action plays an important role in pancreatic β-cell function and survival; thus, it is considered a potential therapeutic target for the treatment of type 2 diabetes in women. However, the mechanisms underlying the protective effects of ERα remain unclear. Because ERα regul...

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Αποθηκεύτηκε σε:
Λεπτομέρειες βιβλιογραφικής εγγραφής
Τόπος έκδοσης:J Biol Chem
Κύριοι συγγραφείς: Zhou, Zhenqi, Ribas, Vicent, Rajbhandari, Prashant, Drew, Brian G., Moore, Timothy M., Fluitt, Amy H., Reddish, Britany R., Whitney, Kate A., Georgia, Senta, Vergnes, Laurent, Reue, Karen, Liesa, Marc, Shirihai, Orian, van der Bliek, Alexander M., Chi, Nai-Wen, Mahata, Sushil K., Tiano, Joseph P., Hewitt, Sylvia C., Tontonoz, Peter, Korach, Kenneth S., Mauvais-Jarvis, Franck, Hevener, Andrea L.
Μορφή: Artigo
Γλώσσα:Inglês
Έκδοση: American Society for Biochemistry and Molecular Biology 2018
Θέματα:
Molecular Bases of Disease
Διαθέσιμο Online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5880140/
https://ncbi.nlm.nih.gov/pubmed/29378845
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M117.805069
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