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Mitochondrial adaptation in obesity is a ClpPicated business

Quality control systems that maintain mitochondrial oxidative phosphorylation (OXPHOS) include rescue by mitochondrial fusion, elimination of dysfunctional mitochondria by mitophagy, and degradation of damaged proteins by proteases. ClpP is an ATP‐dependent protease located in the mitochondrial matr...

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Detalhes bibliográficos
Publicado no:EMBO Rep
Main Authors: Liesa, Marc, Shirihai, Orian S
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5989752/
https://ncbi.nlm.nih.gov/pubmed/29789387
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embr.201846295
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