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Mitochondrial adaptation in obesity is a ClpPicated business

Quality control systems that maintain mitochondrial oxidative phosphorylation (OXPHOS) include rescue by mitochondrial fusion, elimination of dysfunctional mitochondria by mitophagy, and degradation of damaged proteins by proteases. ClpP is an ATP‐dependent protease located in the mitochondrial matr...

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Bibliographic Details
Published in:EMBO Rep
Main Authors: Liesa, Marc, Shirihai, Orian S
Format: Artigo
Language:Inglês
Published: John Wiley and Sons Inc. 2018
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5989752/
https://ncbi.nlm.nih.gov/pubmed/29789387
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embr.201846295
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