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PROTAC-induced BET protein degradation as a therapy for castration-resistant prostate cancer
Prostate cancer has the second highest incidence among cancers in men worldwide and is the second leading cause of cancer deaths of men in the United States. Although androgen deprivation can initially lead to remission, the disease often progresses to castration-resistant prostate cancer (CRPC), wh...
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| Udgivet i: | Proc Natl Acad Sci U S A |
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| Main Authors: | , , , , , , , , , , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
National Academy of Sciences
2016
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4932933/ https://ncbi.nlm.nih.gov/pubmed/27274052 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1521738113 |
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