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Global identification of hnRNP A1 binding sites for SSO-based splicing modulation
BACKGROUND: Many pathogenic genetic variants have been shown to disrupt mRNA splicing. Besides splice mutations in the well-conserved splice sites, mutations in splicing regulatory elements (SREs) may deregulate splicing and cause disease. A promising therapeutic approach is to compensate for this d...
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| Publicado no: | BMC Biol |
|---|---|
| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BioMed Central
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4932749/ https://ncbi.nlm.nih.gov/pubmed/27380775 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12915-016-0279-9 |
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