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HnRNP C, YB-1 and hnRNP L coordinately enhance skipping of human MUSK exon 10 to generate a Wnt-insensitive MuSK isoform

Muscle specific receptor tyrosine kinase (MuSK) is an essential postsynaptic transmembrane molecule that mediates clustering of acetylcholine receptors (AChR). MUSK exon 10 is alternatively skipped in human, but not in mouse. Skipping of this exon disrupts a cysteine-rich region (Fz-CRD), which is e...

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Detalhes bibliográficos
Main Authors: Nasrin, Farhana, Rahman, Mohammad Alinoor, Masuda, Akio, Ohe, Kenji, Takeda, Jun-ichi, Ohno, Kinji
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4213890/
https://ncbi.nlm.nih.gov/pubmed/25354590
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep06841
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