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Competitive regulation of alternative splicing and alternative polyadenylation by hnRNP H and CstF64 determines acetylcholinesterase isoforms
Acetylcholinesterase (AChE), encoded by the ACHE gene, hydrolyzes the neurotransmitter acetylcholine to terminate synaptic transmission. Alternative splicing close to the 3΄ end generates three distinct isoforms of AChE(T), AChE(H) and AChE(R). We found that hnRNP H binds to two specific G-runs in e...
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| Publicat a: | Nucleic Acids Res |
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| Autors principals: | , , , , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Oxford University Press
2017
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5388418/ https://ncbi.nlm.nih.gov/pubmed/28180311 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkw823 |
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