hnRNP A1 and hnRNP F Modulate the Alternative Splicing of Exon 11 of the Insulin Receptor Gene

Exon 11 of the insulin receptor gene (INSR) is alternatively spliced in a developmentally and tissue-specific manner. Linker scanning mutations in a 5′ GA-rich enhancer in intron 10 identified AGGGA sequences that are important for enhancer function. Using RNA-affinity purification and mass spectrom...

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Main Authors: Talukdar, Indrani, Sen, Supriya, Urbano, Rodolfo, Thompson, James, Yates, John R., Webster, Nicholas J. G.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2011
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3223206/
https://ncbi.nlm.nih.gov/pubmed/22132154
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0027869
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