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SRp20 and CUG-BP1 Modulate Insulin Receptor Exon 11 Alternative Splicing

The insulin receptor (IR) exists as two isoforms, IR-A and IR-B, which result from alternative splicing of exon 11 in the primary transcript. This alternative splicing is cell specific, and the relative proportions of exon 11 isoforms also vary during development, aging, and different disease states...

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Autors principals: Sen, Supriya, Talukdar, Indrani, Webster, Nicholas J. G.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology (ASM) 2009
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2630670/
https://ncbi.nlm.nih.gov/pubmed/19047369
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.01709-08
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