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SRp20 and CUG-BP1 Modulate Insulin Receptor Exon 11 Alternative Splicing

The insulin receptor (IR) exists as two isoforms, IR-A and IR-B, which result from alternative splicing of exon 11 in the primary transcript. This alternative splicing is cell specific, and the relative proportions of exon 11 isoforms also vary during development, aging, and different disease states...

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Detalhes bibliográficos
Main Authors: Sen, Supriya, Talukdar, Indrani, Webster, Nicholas J. G.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2630670/
https://ncbi.nlm.nih.gov/pubmed/19047369
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.01709-08
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