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Breaking Cryo-EM Resolution Barriers to Facilitate Drug Discovery
Recent advances in single-particle cryoelecton microscopy (cryo-EM) are enabling generation of numerous near-atomic-resolution structures for well-ordered protein complexes with sizes ≥ ~200 kDa. Whether cryo-EM methods are equally useful for high-resolution structural analysis of smaller, dynamic p...
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| Pubblicato in: | Cell |
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| Autori principali: | , , , , , , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2016
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4931924/ https://ncbi.nlm.nih.gov/pubmed/27238019 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2016.05.040 |
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