Breaking Cryo-EM Resolution Barriers to Facilitate Drug Discovery

Recent advances in single-particle cryoelecton microscopy (cryo-EM) are enabling generation of numerous near-atomic-resolution structures for well-ordered protein complexes with sizes ≥ ~200 kDa. Whether cryo-EM methods are equally useful for high-resolution structural analysis of smaller, dynamic p...

Popoln opis

Shranjeno v:
Bibliografske podrobnosti
izdano v:Cell
Main Authors: Merk, Alan, Bartesaghi, Alberto, Banerjee, Soojay, Falconieri, Veronica, Rao, Prashant, Davis, Mindy, Pragani, Rajan, Boxer, Matthew, Earl, Lesley A., Milne, Jacqueline L.S., Subramaniam, Sriram
Format: Artigo
Jezik:Inglês
Izdano: 2016
Teme:
Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4931924/
https://ncbi.nlm.nih.gov/pubmed/27238019
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2016.05.040
Oznake: Označite
Brez oznak, prvi označite!

Podobne knjige/članki