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2.2 Å resolution cryo-EM structure of β-galactosidase in complex with a cell-permeant inhibitor
Cryo-electron microscopy (cryo-EM) is rapidly emerging as a powerful tool for protein structure determination at high resolution. Here, we report the structure of a complex between Escherichia coli β-galactosidase and the cell-permeant inhibitor phenylethyl β-d-thiogalactopyranoside (PETG), determin...
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| Publié dans: | Science |
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| Auteurs principaux: | , , , , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
2015
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6512338/ https://ncbi.nlm.nih.gov/pubmed/25953817 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.aab1576 |
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