Hepatic Cytochrome P450 Activity, Abundance, and Expression Throughout Human Development

Cytochrome P450s are oxidative metabolic enzymes that play critical roles in the biotransformation of endogenous compounds and xenobiotics. The expression and activity of P450 enzymes varies considerably throughout human development; the deficit in our understanding of these dynamics limits our abil...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Drug Metab Dispos
Egile Nagusiak: Sadler, Natalie C., Nandhikonda, Premchendar, Webb-Robertson, Bobbie-Jo, Ansong, Charles, Anderson, Lindsey N., Smith, Jordan N., Corley, Richard A., Wright, Aaron T.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: The American Society for Pharmacology and Experimental Therapeutics 2016
Gaiak:
Special Section on Pediatric Drug Disposition and Pharmacokinetics
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4931891/
https://ncbi.nlm.nih.gov/pubmed/27084891
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/dmd.115.068593
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