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High-fat diets alter the modulatory effects of xenobiotics on cytochrome P450 activities

Cytochrome P450 monooxygenase (P450) enzymes metabolize critical endogenous chemicals and oxidize nearly all xenobiotics. Dysregulated P450 activities lead to altered capacity for drug metabolism and cellular stress. The effects of mixed exposures on P450 expression and activity are variable and elu...

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Bibliografische gegevens
Gepubliceerd in:Chem Res Toxicol
Hoofdauteurs: Sadler, Natalie C., Webb Robertson, Bobbie-Jo M., Clauss, Therese R., Pounds, Joel G., Corley, Richard, Wright, Aaron T.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2018
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7075635/
https://ncbi.nlm.nih.gov/pubmed/29688711
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.chemrestox.8b00008
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